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Barry and Judy Silverman
College of Pharmacy
College of Pharmacy
Professor
Pharmacy
Barry and Judy Silverman College of Pharmacy
Fort Lauderdale/Davie
The career goals I pursue are to make meaningful contributions to the body of scientific knowledge applicable to human health and to teach and train students and fellows to continue this quest. I teach Bioethics and Pharmacology, with emphasis on Neuro and cardiovascular pharmacology. My research studies the pathophysiological mechanisms by which the renin-angiotensin system (RAS) affects the body. An additional focus of my research is the development and application of radioligands for use in receptor and enzyme binding studies. Notable discoveries include the first report of AT1 and AT2 receptor subtype distribution in the brain, providing the radioligand and cultured cells used to clone the AT2 receptor, the first receptor autoradiography of the AT4 receptor subtype, characterization of the mas protein as the angiotensin (1-7) receptor, and identifying the enzyme neurolysin as an additional binding site for angiotensin peptides. Currently my lab studies enzymes of the metabolic pathways of the RAS and involvement of the RAS in cognitive function. I have coauthored more than 180 peer-reviewed scientific articles that can be accessed at www.pubmed.gov by searching for Speth R. In addition, I have academic interests in the subject of misrepresentation and misuse of dietary supplements and drugs, advocating for the humane use of animals in biomedical research and other animal enterprises, and the integration of arts into the sciences.
Receptor pharmacology, Neuroscience, regulation of the cardiovascular system, radioligand binding, receptor autoradiography, renin-angiotensin system, biased agonism behavior of G protein coupled receptors
Research Interests keywords:
Brain, Central Nervous System, Pharmacology, Receptors, Radioligands, Renin-Angiotensin System, Receptor autoradiography, Radioligand binding assays, Hypertension, Cardiovascular disease, immunohistochemistry
Research in Pharmaceutical Sciences PHA 5999 Elective Hands-on Students are involved in planning and executing an approved research project studying Cardiovascular Neuroscience and Pharmacology, with a focus on neurohormone receptor-ligand interactions using basic and advanced techniques of scientific research. (3-4 cr)
Literature Research in Sciences PHA 5993 Elective Didactic Directed reading, evaluation and analysis of scientific literature in the field of Neuropharmacology, Bioethics, Biotechnology, Toxicology, Dietary Supplements, Integrative Health and others. Students are mentored and trained in retrieval of scientific information, building hypotheses, writing papers and reviewing manuscripts.
Drug Literature Evaluation PHA 6610 Required P3 Didactic This course provides a framework to guide the student through the thought processes necessary to evaluate different types of medical information. The student is able to apply learned techniques in information retrieval, evaluation and communication by conducting actual literature evaluations on relevant therapeutic topics.
Advance Practice Experience Research Elective PHA7860/7880 Elective Practice Experience Students may elect to work on a faculty directed research project during the APPE component of their P4 year.
Poster Project PHA 6630 Required P3 Special Projects All students complete a literature review research project as part of Therapeutics and Pathophysiology III.
Faculty Research NA Elective Volunteer Students may volunteer to work with Dr. Speth on a research project related to Cardiovascular Neuroscience and Pharmacology.
Faculty Research NA Elective Work-study Student workers may be hired to work with Dr. Speth on a research project related to Cardiovascular Neuroscience and Pharmacology.
NRSA Post-Doctoral Fellow 1978; Adjunct Asst. Professor, Dept. Pharmacology, Univ.Arizona School of Medicine, Tucson, AZ 1979; Associate Staff, Cleveland Clinic, Cleveland, OH 1979-1984; Associate/Full Professor/Graduate Faculty: Department of Vet. Comp. Anat., Pharmacol. Physiol. (VCAPP), Pharmacology/Toxicology and Neuroscience Programs, Washington State Univ., Pullman, WA 1984-2003; Director, Peptide Radioiodination Service Center: Washington State University, Pullman, WA, Univ Mississippi, 1991-2009; Fellow, AAAS 1996; 1999-2000 Visiting Scientist, Oregon Health Sciences University, Beaverton, OR 1999-2000; Chair/Professor, Dept. Pharmacology, School of Pharmacy, Univ.Mississippi, University MS 2003-2009; Professor of Pharmaceutical Sciences, College of Pharmacy, Nova Southeastern Univ, Fort Lauderdale, FL 2009-present; Courtesy Professor, Dept. Physiology and Functional Genomics, Univ. Florida, Gainesville, FL 2012-present; Adjunct Professor of Pharmacology and, College of Medicine, Georgetown Univ. Washington, DC 2013-present. Awards: Lewis J. Kettle Award: Incurably Ill for Animal Research (October 1998); Dr. T.S. Williams Lecturer Award: Tuskegee Veterinary Medical Alumni Assoc. (March 1998); Washington State Univ. Faculty Library Awards Washington State Univ. (April 1999, June 2003) Keynote Speaker Tri-Beta Induction Ceremony Farquhar College of Arts and Sciences, Nova Southeastern University April 10, 2014.
Recent honors:
(October, 2016) 2016 Provost’s Research and Scholarship Award, Nova Southeastern University
(January, 2017) Million Dollar Club Award, College of Pharmacy, Nova Southeastern
University
(May, 2017) 2017 World Class Faculty Award, Greater Fort Lauderdale Alliance, Fort
Lauderdale, FL.
Robert C. Speth, Ph.D.
Office: 1348A, Terry Building
Lab: 3307A, HPD Library Annex Building
Office phone: 954-262-1330
Lab phone: 954-262-7308
Cell phone: 662-291-2014
Date Posted: 05/22/2017